A6938
Sigma

Pituitary adenylate cyclase activating polypeptide amide fragment 6-27

Synonym

PACAP-6-27

Amino Acid Sequence

Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH₂

Molecular Formula

C₁₂₁H₁₉₃N₃₃O₃₁S

Molecular Weight

2638.09

CAS Number

136134-68-4

MDL number

MFCD00145059

Expand/Collapse All

Descriptions

Biochem/physiol Actions

Inhibitor of PACAP-27.

Properties

composition

Peptide content, ~65%

Gene Information

human ... ADCYAP1(116)

storage temp.

−20°C

References

Reference

Filipsson, K., et al., PACAP contributes to insulin secretion after gastric glucose gavage in mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 279, R424-R432, (2000) abstract

Robberecht, P., et al., Receptor occupancy and adenylate cyclase activation in AR 4-2J rat pancreatic acinar cell membranes by analogs of pituitary adenylate cyclase-activating peptides amino-terminally shortened or modified at position 1, 2, 3, 20, or 21. Mol. Pharmacol. 42, 347-355, (1992) abstract

Gaspo, R., et al., Canine adrenal catecholamine response to VIP is blocked by PACAP-(6-27) in vivo. Am. J. Physiol. 272, R1606-R1612, (1997) abstract

Safety

WGK Germany

Related Categories

... Miscellaneous Peptides > Adenylate Cyclase Activators

... Cyclic Nucleotide Metabolism > Adenylyl Cyclase Activators

... Peptides for Cell Biology > Vasoactive Intestinal Peptides

MSDS

Certificate of Analysis

More Information

Related Categories

Printer Friendly View

Ask A Scientist

Email Page

Last 5 Products Viewed

A6938 (Sigma)