A7929
Sigma

L-(+)-2-Amino-4-phosphonobutyric acid

optical purity optical purity: ≥95% (HPLC, Marfey's reagent)

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Synonym

L-AP-4

Molecular Formula

C₄H₁₀NO₅P

Molecular Weight

183.10

CAS Number

23052-81-5

MDL number

MFCD00083244

PubChem Substance ID

24891296

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Descriptions

Biochem/physiol Actions

mGluR₄ and mGluR₆ metabotropic glutamate receptor agonist.

Properties

optical purity

optical purity: ≥95% (HPLC, Marfey's reagent)

References

Reference

Saugstad, et al., Cloning and expression of a new member of the L-2-amino-4-phosphono-butyric acid-sensitive class of metabotropic glutamate receptors. Mol. Pharmacol. 45, 367, (1994) abstract

Kristensen, et al., Expression pattern and pharmacology of the rat type IV metabotropic glutamate receptor. Neurosci. Lett. 155, 159, (1993) abstract

Nakajima, et al., Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR 6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate. J. Biol. Chem. 268, 11868, (1993) abstract

Safety

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

Related Categories

... Excitatory Amino Acids > Metabotropic Agonists

Glutamate Receptors G Protein Family (193 kb)

MSDS

Certificate of Analysis

More Information