A9630
Sigma

4-Androstene-3,17-dione

≥98%

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Synonym

Androstenedione

Molecular Formula

C₁₉H₂₆O₂

Molecular Weight

286.41

CAS Number

63-05-8

Beilstein Registry Number

2059239

MDL number

MFCD00003615

PubChem Substance ID

24278247

EG/EC Number

200-554-5

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Descriptions

Biochem/physiol Actions

Testosterone precursor and metabolite with androgenic activity; may increase the risk of prostate or pancreatic cancer.

Properties

assay

≥98%

drug control

USDEA Schedule III; Home Office Schedule 4.2

170-171 °C(lit.)

Gene Information

human ... HSD17B3(3293)

References

Reference

Provost, P.R., Androgen formation and metabolism in the pulmonary epithelial cell line A549: expression of 17β-hydroxysteroid dehydrogenase type 5 and 3α-hydroxysteroid dehydrogenase type 3. Endocrinology 141, 2786, (2000) abstract

O'Shaughnessy, P.J., Localization of 17β-hydroxysteroid dehydrogenase/17-ketosteroid reductase isoform expression in the developing mouse testis--androstenedione is the major androgen secreted by fetal/neonatal leydig cells. Endocrinology 141, 2631, (2000) abstract

Hagemeyer, C.E., et al., Different testosterone metabolism by immortalized embryonic and postnatal hippocampal neurons from C57BL/6 mice: a crucial role for androstenedione. J. Neurosci. 60, 106-115, (2000)

Merck

Merck 13,643

Beilstein

Beil. 7,IV,2381

reference

Corp MSDS 1, 263:B / FT-IR 2 (3), 4236:B / FT-NMR 1 (3), 588:A / RegBook 1 (2), 2865:G / Sigma FT-IR 1 (1), 1196:B / Structure Index 1, 459:D:1

Safety

Safety Statements

22-24/25

WGK Germany

RTECS

BV8150000