A9810
Sigma

Amyloid β Protein Fragment 1-42

Amino Acid Sequence

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala

Molecular Formula

C₂₀₃H₃₁₁N₅₅O₆₀S

Molecular Weight

4514.04

CAS Number

107761-42-2

MDL number

MFCD00163049

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Descriptions

Biochem/physiol Actions

The predominant fragment of amyloid β-protein found in the brains of patients with Alzheimer's disease and Down's syndrome.

Properties

Gene Information

human ... APP(351)

storage temp.

−20°C

References

Reference

Jarrett, J.T., et al., The carboxy terminus of the β-amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 32, 4693-4697, (1993) abstract

Safety

WGK Germany