| A9920 Sigma |
β-Alaninecell culture tested, insect cell culture tested |
Synonym
β-Ala
3-Aminopropionic acid
Molecular Formula
NH2CH2CH2COOH
Molecular Weight
89.09
CAS Number
Beilstein Registry Number
906793
MDL number
PubChem Substance ID
EG/EC Number
203-536-5
Descriptions
Biochem/physiol Actions
Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.
Packaging
10 mg in autosmp vl
References
Reference
Hoeger, U., and Abe, H., β-Alanine and other free amino acids during salinity adaptation of the polychaete Nereis japonica. Comp. Biochem. Physiol. 137, 161-171, (2004)
Vairetti, M., et al., β-alanine protection against hypoxic liver injury in the rat. Biochim. Biophys. Acta 1587, 83-91, (2002)
Pullan, L.M., and Powel, R.J., Comparison of binding at strychnine-sensitive (inhibitory glycine receptor) and strychnine-insensitive (N-methyl-D-aspartate receptor) glycine binding sites. Neurosci. Lett. 148, 199-201, (1992)
Shinohara, T., et al., Identification of a G protein-coupled receptor specifically responsive to β-alanine. J. Biol. Chem. 279, 23559-23564, (2004)
Hammer, M.A., and Baltz, J.M., β-alanine but not taurine can function as an organic osmolyte in preimplantation mouse embryos. Mol. Reprod. Dev. 66, 153-161, (2003)
Merck
Merck 13,204
Beilstein
Beil. 4,IV,2526
Fieser
Fieser 1,16 / Fieser 5,6 / Fieser 6,10 / Fieser 17,3
reference
Corp MSDS 1 (1), 84:D / FT-IR 2 (1), 916:D / FT-IR 1 (1), 572:A / FT-NMR 1 (1), 877:A / Fenaroli, 17 / IR-Spectra (3), 342:C / IR-Spectra (2), 305:C / NMR-Reference 2 (1), 486:C / RegBook 1 (1), 657:N / Sigma FT-IR 1 (1), 19:C / Structure Index 1, 97:A:5
Related InformationCertificate of Analysis
Certificate of Origin
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