B174
Sigma

BIBP 3226

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Synonym

N2-(Diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-D-arginine amide

Molecular Formula

C₂₇H₃₁N₅O₃

Molecular Weight

473.57

CAS Number

159013-54-4

MDL number

MFCD00938562

PubChem Substance ID

24891607

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Descriptions

Biochem/physiol Actions

Selective non-peptide neuropeptide Y₁ (NPY₁) receptor antagonist.

Properties

assay

≥95%

solubility

H₂O: 1 mg/mL

storage temp.

−20°C

References

Reference

Vanderheyden, et al., Non-competitive binding of the nonpeptide antagonist BIBP3226 to rat forebrain neuropeptide Y receptors. Eur. J. Pharmacol. 331, 275-284, (1997) abstract

Tough, et al., Selective inhibition of neuropeptide Y Y1 receptors by BIBP3226 in rat and human epithelial preparations. Eur. J. Pharmacol. 310, 55-60, (1996) abstract

Doods, et al., Pharmacological characterization of the selective nonpeptide neuropeptide Y Y₁ receptor antagonist BIBP 3226. J. Pharmacol. Exp. Ther. 275, 136-142, (1995) abstract

Safety

WGK Germany

Related Categories

... Neuropeptide Y and Peptide YY Peptides > Neuropeptide Y

... Neurotransmission (Obesity) > Neuropeptide Y and Peptide YY

MSDS

Certificate of Analysis

Certificate of Origin

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