B5182
Sigma

7-Benzyloxyquinoline

99% (by ¹H-NMR), solid

Molecular Formula

C₁₆H₁₃NO

Molecular Weight

235.28

CAS Number

131802-60-3

MDL number

MFCD00870296

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Descriptions

Biochem/physiol Actions

Fluorogenic substrate for CYP3A4.

Properties

assay

99% (by ¹H-NMR)

form

solid

storage temp.

−20°C

References

Reference

Stresser, D. M., Substrate-dependent modulation of CYP3A4 catalytic activity: analysis of 27 test compounds with four fluorometric substrates. Drug Metab. Dispos. 28, 1440, (2000)

Lu, P., et al., Testosterone, 7-benzyloxyquinoline, and 7-benzyloxy-4-trifluoromethyl-coumarin bind to different domains within the active site of cytochrome P450 3A4. Drug Metab. Dispos. 29(11), 1473-1479, (2001)

Safety

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany