Monoclonal Anti-CD11b antibody produced in mouse 

CD11b α-chain of the human CD11b/CD18 complex is an α/β heterodimeric glycoprotein which belongs to the β₂ integrin family. It is also known as Mac-1, CR3, MO-1 and C3bi receptor. CD11b is expressed on the surface of circulating monocytes, granulocytes and certain NK cells and is also present in subsets of macrophages. It functions as a receptor for iC3b, clotting factor X, fibrinogen and ICAM-1.

human monocytes.

Recognizes the CD11b α-chain of the human CD11b/CD18 complex. The antibody is useful for studies on cell adhesion and migration and for the detection of leukocyte adhesion deficiencies. It may be used to stain acetone-fixed cryostat sections or cell preparations. The epitope recognized by the antibody is formalin sensitive.
2nd Workshop: code no. M104
3rd Workshop: code no. 202 and 238
4th Workshop: code no. M47

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

purified immunoglobulin

ICRF44

buffered aqueous solution

antigen mol wt 165-170 kDa

human

flow cytometry: 5 μL using 1 × 10⁶ cells

IgG1

human ... ITGAM(3684)

wet ice

2-8°C

Malhotra, V., et al. Eur. J. Immunol. 16, 1117, (1986)

Myones, B.L. J. Clin. Invest. 82, 640, (1988)

Knapp, W., et al. Leucocyte Typing IV Oxford , (1989)

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