C1254
Sigma

Sodium cholate hydrate

from ox or sheep bile, ≥99%

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Synonym

Cholalic acid sodium salt

3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt

Molecular Formula

C₂₄H₃₉NaO₅ · xH₂O

Molecular Weight

430.55 (anhydrous basis)

CAS Number

206986-87-0

Beilstein Registry Number

3582354

MDL number

MFCD00150749

PubChem Substance ID

24892390

EG/EC Number

206-643-5

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Descriptions

Application

Non-denaturing detergent used for extraction of membrane proteins.

Biochem/physiol Actions

Bile Salt

Properties

biological source

from ox or sheep bile

assay

≥99%

mol wt

micellar avg mol wt 900-1300

aggregation number

2-3

CMC

9-15 mM(20-25°C)

HLB

References

Reference

A. Helenius Meth. Enzymol. 56, 734, (1979)

Ozols, J., Preparation of membrane fractions. Meth. Enzymol. 182, 225-235, (1990)

L.M. Hjelmeland, A. Chrambach Meth. Enzymol. 104, 305, (1984)

C.V. Nicchitta, G. Blobel Cell 60, 259, (1990) abstract

J.C. Gordon Eur. J. Pharmacol., Molec. Pharmacol. Sec. 188, 313, (1990)

Hori, H., et al., Isolation and characterization of two 20S proteasomes from the endoplasmic reticulum of rat liver microsomes. J. Biochem. (Tokyo) 126, 722-730, (1999)

Beilstein

Beil. 10,III,2166 / Beil. 10,IV,2073

reference

RegBook 1 (2), 2869:J / Sigma FT-IR 1 (1), 1222:A / Structure Index 1, 459:A:8

Safety

WGK Germany

3-9

Related Categories

... Sterols > Bile acids and Derivatives

... Anionic > Bile Salts

... Essential Biological Reagents > Detergents

... Detergents > Detergents A to Z

... Cell Lysis and Protein Extraction Reagents > Detergents for Cell Lysis

FT-IR Raman

MSDS

Specification Sheet

Certificate of Analysis

Certificate of Origin

More Information