C4235
Sigma

Cytochrome P450 human

2C9*2 Isozyme Microsomes, with P450 Reductase, recombinant, expressed in baculovirus infected insect cells (BTI-TN-5B1-4)

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MDL number

MFCD03456520

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Descriptions

Biochem/physiol Actions

The CYP2C9*2 isoform catalyzes the 4-hydroxylation of diclofenac.

Preparation Note

Microsomes containing human CYP2C9*2 and recombinant human NADPH-P450 reductase.

Physical form

Solution in 100 mM Tris-HCl buffer, pH 7.5.

Properties

recombinant

expressed in baculovirus infected insect cells (BTI-TN-5B1-4)

packaging

vial of 1.0 nmol

Gene Information

human ... CYP2C9(1559)

shipped in

dry ice

storage temp.

−70°C

References

Reference

Shimamato, J., Lack of differences in diclofenac (a substrate for CYP2C9) pharmacokinetics in healthy volunteers with respect to the single CYP2C9*3 allele. Eur. J. Clin. Pharmacol. 56, 65, (2000) abstract

Safety

WGK Germany

C4235 - Datasheet (53kb)

MSDS

Certificate of Analysis

More Information