C4354
Sigma

Cytokine-Induced Neutrophil Chemoattractant-3 from rat

>97% (SDS-PAGE), recombinant, expressed in Escherichia coli, lyophilized powder, cell culture tested

Synonym

CINC-3

MIP-2

MDL number

MFCD02687285

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Descriptions

Analysis Note

The biological activity is measured by its ability to induce myeloperoxidase release from cytochalasin B treated human neutrophils.

Physical form

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 1.25 mg bovine serum albumin.

Biochem/physiol Actions

CINC-3, a member of the α (CXC) subfamily of chemokines, is a potent chemotactic factor for rat neutrophils in vivo and in vitro. Rat and murine CINC-3 exhibits approximately 88% homology.

Properties

recombinant

expressed in Escherichia coli

assay

>97% (SDS-PAGE)

form

lyophilized powder

total impurities

Endotoxin, tested

suitability

cell culture tested

Gene Information

rat ... Cxcl2(114105)

storage temp.

−20°C

References

Reference

Schroder, J. et al., Purification and partial biochemical characterization of a human monocyte-derivedneutrophil-activating peptide that lacks interleukin 1 activity. J. Immunol. 139, 3474-3483, (1987) abstract

Huang, S. et al., Expression of macrophage inflammatory protein-2 and KC mRNA in pulmonary inflammation. Am. J. Pathol. 141, 981-988, (1992) abstract

Safety

WGK Germany

Related Categories

... Chemokines > Cytokine-Induced Neutrophil Chemoattractant

C4354 - Datasheet (58kb)

MSDS

Certificate of Analysis

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