C4428
Sigma

Cathepsin�G from human leukocytes

lyophilized powder, ≥60 units/mg protein (Bradford)

CAS Number

107200-92-0

Enzyme Commission (EC) Number

3.4.21.20 ( BRENDA | IUBMB )

MDL number

MFCD00130750

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Descriptions

Biochem/physiol Actions

Cathepsin G has pro-apoptotic activity and can activate caspases in vitro.

Unit Definition

One unit will release one nanomole of p-nitroaniline per second from N-succinyl-Ala-Ala-Pro-Phe p-nitroanilide at pH�7.5 at 37�°C.

Physical form

Lyophilized from 0.5 M pyridinium acetate, pH 5.3.

Properties

form

lyophilized powder

Gene Information

human ... CTSG(1511)

shipped in

dry ice

storage temp.

−20°C

References

Reference

Bird, P.I., Regulation of pro-apoptotic leukocyte granule serine proteinases by intracellular serpins. Immunol. Cell Biol. 77, 47-57, (1999) abstract

Tang, J., Evolution in the structure and function of carboxyl proteases. Mol. Cell Biochem. 26, 93-109, (1979) abstract

Barrett, A.J, Cathepsin G. Meth. Enzymol. 80, 561-565, (1981) abstract

Safety

Hazard Codes

Safety Statements

22-24/25

WGK Germany