C4618
Sigma

Monoclonal Anti-Cathepsin L antibody produced in mouse

~2 mg/mL, clone CPL33/1, purified immunoglobulin, buffered aqueous solution

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Synonym

Anti-CATL

Anti-CTSL

Anti-MEP

MDL number

MFCD01321805

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Descriptions

Immunogen

human procathepsin L. The antibody epitope resides within amino acids 258-261 of human cathepsin L (FYKE).

Specificity

The antibody recognizes the native and denaturated forms of the protein¹ and does not cross react with human cathepsin V.²

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Properties

antibody form

purified immunoglobulin

clone

CPL33/1

form

buffered aqueous solution

mol wt

antigen mol wt ~25 kDa (human cathepsin L)

antigen mol wt ~42 kDa (human pro cathepsin L)

species reactivity

human

concentration

~2 mg/mL

application(s)

immunoblotting^1,²: 0.1-0.2 μg/mL using total cell extracts of A549 cells

immunohistochemistry²: suitable

indirect ELISA¹: suitable

isotype

IgG1

Gene Information

human ... CTSL1(1514)

shipped in

dry ice

storage temp.

−20°C

References

Cited Reference

1. Weber, E., et al. Hybridoma 16, 159-165, (1997)

2. Tolosa, E., et al. Clin. Invest. Med. 112, 517-526, (2003)

Safety

WGK Germany