C5232
Sigma

Cytochrome P450 human

2D6 Isozyme Microsomes, with P450 Reductase, recombinant, expressed in baculovirus infected Sf9 cells

MDL number

MFCD03456520

Descriptions

Other Notes

Microsomes containing recombinant human CYP2D6 and recombinant rabbit NADPH-P450 reductase.

Unit Definition

One unit will hydroxylate 1 nanomole of bufuralol per minute at pH 7.4 at 37 °C.

Physical form

Solution in 100 mM potassium phosphate buffer, 0.1 mM EDTA, 1.0 mM DTT, 20% (v/v) gycerol, pH 7.4.

Properties

recombinant

expressed in baculovirus infected Sf9 cells

packaging

vial of 0.5 nmol

shipped in

dry ice

storage temp.

−70°C

Safety

Safety Statements

23-24/25

WGK Germany

Related Categories

... Xenobiotics and Drug Metabolism > Cytochrome P450s (CYPs)

... Drug and Xenobiotic Metabolism > Oxidative Pathway

... Enzymes > Phase I Enzymes

... Multidrug Resistance > Phase I Enzymes

MSDS

Certificate of Analysis