Monoclonal Anti-CXCR-1 (IL-8 RA) antibody produced in mouse 

human CXCR1 transfected NSO mouse myeloma cells.

Purified using protein G.

The antiboody, in the presence of anti-CXCR2 (Sigma Product No. C6348), will neutralize human cell surface CXCR-1 mediated-myloperoxidase release from human granulocytes induced by IL-8. The antibody reacts with human CXCR1 transfectant cells and not the parent cell line. The antibody shows no cross-reactivity with CXCR2.

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

purified immunoglobulin

42705.111

lyophilized powder

human

flow cytometry: 10 μg/mL using using human blood cells (10 μL diluted antibody/10⁵-10⁶ cells)

immunohistochemistry (frozen sections): 25 μg/mL using human tissue (speen)

neutralization: suitable

IgG2a

mouse ... Il8ra(227288)

human ... IL8RA(3577)

−20°C

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