C6348
Sigma

Monoclonal Anti-CXCR2 (IL-8 RB) antibody produced in mouse

clone 48311.211, purified immunoglobulin, lyophilized powder

MDL number

MFCD01864633

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Descriptions

Immunogen

human CXCR2 transfected NSO mouse myeloma cells.

Preparation Note

Purified using protein G.

Specificity

The antibody will neutralize human cell surface CXCR-2 mediated-myloperoxidase release from human granulocytes induced by GROα. It will not block myeloperoxidase release induced by IL-8. The antibody reacts with human CXCR-2 transfectant cells and not the parent cell line. The antibody shows no cross-reactivity with CXCR-1.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Properties

antibody form

purified immunoglobulin

clone

48311.211

form

lyophilized powder

species reactivity

human

application(s)