Monoclonal Anti-CD44 antibody produced in mouse 

The CD44 antigen has been studied under the following names: Pgp-1, Hermes antigen, ECM-III, H-CAM and HUTCH-1. It functions as a homing receptor. CD44 antigen is the cellular receptor for hyaluronic acid. The antibody is also reactive with bone marrow nucleated cells, medullary thymocytes, liver Kupffer cells, fibroblasts, corneal cells, epidermal keratinocytes, synovial cells, a subset of pancreatic acinar cells and brain cells.

circulating malignant human Sezary T cells.

Recognizes the CD44 (80-95 kDa) human cell surface glycoprotein on B and T lymphocytes, monocytes, granulocytes and red blood cells. The epitope recognized by this antibody is sensitive to bromelain and other proteolytic enzymes. It is detectable in routine formalin-fixed, paraffin-embedded tissue.
5th Workshop: code no. BP406, S320

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

purified immunoglobulin

A3D8

buffered aqueous solution

antigen mol wt 80-95 kDa

human

flow cytometry: 5 μL using 1 × 10⁶ cells

IgG1

human ... CD44(960)

wet ice

2-8°C

Haynes, B.F., et al. Immunology Today 10, 423, (1989) abstract

Denning, S.M., et al. J. Immunol. 144, 7, (1990) abstract

Hale, L. P., et al. J. Immunol. 149, 3809, (1992) abstract

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