C8354
Sigma

Anti-CX3CR-1, N-Terminal antibody produced in rabbit

~0.5 mg/mL, affinity isolated antibody, buffered aqueous solution

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MDL number

MFCD02687272

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Descriptions

Immunogen

synthetic peptide corresponding to the N-terminal and amino acids 2-21 of human CX3CR1 (V28, CMKBRL1). This sequence differs from mouse and rat by four amino acids.

Physical form

Solution in 0.01 M phosphate buffered saline containing 0.02% sodium azide.

Properties

antibody form

affinity isolated antibody

form

buffered aqueous solution

mol wt

antigen mol wt 50 kDa

species reactivity

human

concentration

~0.5 mg/mL

application(s)

immunoblotting: 1:500-1:2,000 using a human spleen tissue lysates

Gene Information

mouse ... Cx3cr1(13051)

human ... CX3CR1(1524)

rat ... Cx3cr1(171056)

shipped in

dry ice

storage temp.

−20°C

References

Reference

Raport ,C.J., et al., The orphan G-protein-coupled receptor-encoding gene V28 is closely related to genes for chemokine receptors and is expressed in lymphoid and neural tissues. Gene 163, 295, (1995) abstract

Combadiere, C., et al., Gene cloning RNA distribution and functional expression of mCX3CR1a mouse chemotactic receptor for the CX3C chemokine fractalkine. Biochem. Biophys. Res. Commun. 253, 728, (1998) abstract

Harrison, J.K., et al., cDNA cloning of a G-protein-coupled receptor expressed in rat spinal cord and brain related to chemokine receptors. Neurosci. Lett. 169, 85-89, (1994) abstract

Combadiere, C., et al., Cloning, chromosomal localization, and RNA expression of a human beta chemokine receptor-like gene. DNA Cell. Biol. 14, 673-680, (1995) abstract

Safety

WGK Germany