Antigen Background
CD152, a cell surface glycoprotein, is one of two ligands (the other is CD28) for CD80 (B7-1) and CD86 (B7-2). This interaction appears to function as a negative regulator to T cell activation. CD152 is transiently expressed on activated T cells.
Immunogen
recombinant extracellular domain of human CD152.
Preparation Note
Prepared from tissue culture supernatant, purified using protein G.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 0.08% sodium azide.
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