1α,25-Dihydroxyvitamin D₃ 

Biologically active form of vitamin D₃ in calcium absorption and deposition. 1α,25-Dihydroxyvitamin D₃ has widespread effects on cellular differentiation and proliferation, and can modulate immune responsiveness, and central nervous system function. Recent studies suggest that 1α,25-dihydroxyvitamin D₃ acts as a chemopreventive agent against several malignancies including cancers of the prostate and colon and shows synergy with other anticancer compounds.

≥99% (TLC)

human ... VDR(7421)

2-8°C

Lin, R., and White, J.H., The pleiotropic actions of vitamin D. Bioessays 26, 21-28, (2004)

Jones, G., et al., Current understanding of the molecular actions of vitamin D. Physiol. Rev. 78, 1193-1231, (1998)

DeLuca, H.F., and Cantorna, M.T., Vitamin D: its role and uses in immunology. FASEB J. 15, 2579-2585, (2001)

Merck 13,1643

UN2811 6.1 /PG 1

3

FZ4645000