D2066
Sigma

DAN from mouse

>97% (SDS-PAGE), recombinant, expressed in mouse NSO cells, lyophilized powder

Synonym

Differential Screening-selected Gene Aberrative in Neuroblastoma

MDL number

MFCD03703072

Expand/Collapse All

Descriptions

Analysis Note

The biological activity is measured by its ability to bind BMP-4.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Biochem/physiol Actions

DAN, a member of the DAN family of secreted glycoproteins, is an antagonist for the TGF-β superfamily. DAN binds the TGF-β ligands and prevents their interactions with signaling receptor complexes.

Properties

recombinant

expressed in mouse NSO cells

assay

>97% (SDS-PAGE)

form

lyophilized powder

mol wt

calculated mol wt 18.9 kDa

mol wt 27-30 kDa by SDS-PAGE (reducing)

total impurities

Endotoxin, tested

Gene Information

mouse ... Nbl1(17965)

storage temp.

−20°C

References

Reference

Ozaki, T., et al. Jpn. J. Cancer Res. 87, 58, (1996)

Massage, J., Chen, Y-G. Genes Dev. 14, 627, (2000)

Safety

WGK Germany

Related Categories

... Transforming Growth Factor-β (TGF-β) and Superfamily > TGF-β Inhibitors

... Tyrosine Kinase-Like > Transforming Growth Factor β (TGF-β)

D2066 - Datasheet (26kb)

MSDS

Certificate of Analysis

More Information

Related Categories

Printer Friendly View

Bulk Quote

Ask A Scientist

Last 5 Products Viewed

D2066 (Sigma)