D5385
Sigma

1,7-Dimethylxanthine

~98%, solid

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Synonym

1,7-Dimethyl-1H-purine-2,6-dione

2,6-Dihydroxy-1,7-dimethylpurine

Paraxanthine

Molecular Formula

C₇H₈N₄O₂

Molecular Weight

180.16

CAS Number

611-59-6

Beilstein Registry Number

197907

MDL number

MFCD00005727

PubChem Substance ID

24277678

EG/EC Number

210-271-9

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Descriptions

Biochem/physiol Actions

Adenosine receptor ligand; major metabolite of caffeine

Properties

assay

~98%

form

solid

color

white

294-296 °C(lit.)

solubility

ethanol: 0.6 mg/mL

H₂O: 1 mg/mL

0.1 M NaOH: 2 mg/mL

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)

References

Reference

Shi, et al., Chronic effects of xanthines on levels of central receptors in mice. Cell. Mol. Neurobiol. 19, 719-732, (1999) abstract

Ferre, et al., Paraxanthine displaces the binding of [³H]SCH-23390 from rat striatal membranes. Eur. J. Pharmacol. 179, 295-299, (1990) abstract

Jodynis-Liebert, et al., Effect of toluidines and dinitrotoluenes on caffeine metabolic ratio in rat. Toxicol. Lett. 104, 159-165, (1999) abstract

Beilstein

Beil. 26,IV,2335

reference

FT-NMR 1 (3), 214:A / RegBook 1 (2), 2465:I / Sax 6, 2120 / Sigma FT-IR 1 (1), 992:D / Structure Index 1, 390:A:3

Safety

Hazard Codes

Risk Statements

Safety Statements

22-24/25

WGK Germany

RTECS

RV9380000