D5565
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DNA Arrays: Technologies and Experimental Strategies

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General description

A giant leap in technology took place with the introduction of cDNA arrays that have been developed in response to the need for simultaneous analysis of the patterns of expression of thousands of genes. This book offers a view of different aspects of this rapidly developing technology, including oligonucleotides and electrochemical arrays. Up-to-date insights into methodological fundamentals of construction of DNA arrays, optimization of hybridization conditions, the use of expression data in bioinformatics, different software tools, and the application of microarray technology for drug discovery process are provided.

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Identifiers

ISBN-10

0-8493-2285-5

ISBN-13

978-0-8493-2285-3

Properties

publication info

E.V. Grigorenko, CRC Press, 2001, 356 pp., hard cover

Table of Contents

Introduction Technology Development for DNA Chips,
Experimental Design for Hybridization Array Analysis of Gene Expression,
Nylon Platform: Pros and Cons,
Oligonucleotide Array Technologies for Gene Expression Profiling,
Electrochemical Detection of Nucleic Acids,
DNA Microarrays in Neurobiology, Management in Microarray Fabrication, Image Processing and Data Mining, A. Kuklin, S. Shah, B. Hoff, and S. Shams
Zeroing In on Essential Gene Expression Data,
Application of Arrayed Libraries for Analysis of Differential Gene Expression Followed Chronic Cannabinoid Exposure,
Supplier List List of Web Sites
Related to DNA Arrays
Index