D5816
Sigma

(−)-Depudecin

>95% (HPLC), from microbial

zoom

1 of 1

Synonym

4,5:8,9-Dianhydro-1,2,6,7,11-pentadeoxy-D-threo-D-ido-undeca-1,6-dienitol

Molecular Formula

C₁₁H₁₆O₄

Molecular Weight

212.24

CAS Number

139508-73-9

MDL number

MFCD04039998

PubChem Substance ID

24893973

Expand/Collapse All

Descriptions

Biochem/physiol Actions

Inhibitor of histone deacetylase (HDAC) both in vivo and in vitro. Alters the spindle shaped morphology of v-Ha-ras-transformed NIH3T3 cells to a flattened shape and induces an intricate actin stress fiber network in these cells and in MG63 osteosarcoma cells. Also exhibits anti-angiogenic activity.

Properties

biological source

from microbial

assay

>95% (HPLC)

form

liquid

shipped in

dry ice

storage temp.

−20°C

References