D5891
Sigma

1,1-Dimethyl-4-phenylpiperazinium iodide

≥98% (TLC or titration), powder

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Synonym

DMPP

Molecular Formula

C₁₂H₁₉IN₂

Molecular Weight

318.20

CAS Number

54-77-3

Beilstein Registry Number

3746109

MDL number

MFCD00011976

PubChem Substance ID

24277832

EG/EC Number

200-213-0

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Descriptions

Biochem/physiol Actions

Nicotinic acetylcholine receptor agonist.

Properties

assay

≥98% (TLC or titration)

form

powder

color

white

234-238 °C(lit.)

solubility

H₂O: 21 mg/mL

Gene Information

human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143)

rat ... Chrna2(170945), Chrna3(25101), Chrna4(25590), Chrnb2(54239), Chrnb4(25103)

storage temp.

−20°C

References

Reference

Vizi, E.S., and Lendvai, B., Modulatory role of presynaptic nicotinic receptors in synaptic and non-synaptic chemical communication in the central nervous system. Brain Res. Brain Res. Rev. 30, 219-235, (1999) abstract

Galligan, J.J, Nerve terminal nicotinic cholinergic receptors on excitatory motoneurons in the myenteric plexus of guinea pig intestine. J. Pharmacol. Exp. Ther. 291, 92-98, (1999) abstract

Manetti, D., et al., Hybridized and isosteric analogues of N¹-acetyl-N⁴-dimethyl-piperazinium iodide (ADMP) and N1-phenyl-N4-dimethyl-piperazinium iodide (DMPP) with central nicotinic action. Bioorg. Med. Chem. 7, 457, (1999) abstract

Beilstein

Beil. 23,V,1,171

reference

Aldrich MSDS 1, 794:C / Corp MSDS 1 (1), 1407:C / FT-IR 2 (2), 2245:C / FT-IR 1 (1), 1323:B / IR-Spectra (3), 798:B / IR-Spectra (2), 699:E / RegBook 1 (1), 1539:I / Sax 6, 1191 / Sigma FT-IR 1 (2), 509:B

Safety

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

RTECS

TM3385000