D6189
Sigma

Dendroaspis Natriuretic Peptide trifluoroacetate salt

≥90% (HPLC)

Amino Acid Sequence

Glu-Val-Lys-Tyr-Asp-Pro-Cys-Phe-Gly-His-Lys-Ile-Asp-Arg-Ile-Asn-His-Val-Ser-Asn-Leu-Gly-Cys-Pro-Ser-Leu-Arg-Asp-Pro-Arg-Pro-Asn-Ala-Pro-Ser-Thr-Ser-Ala [Disulfide Bridge: 7-23]

Molecular Formula

C₁₈₀H₂₈₂N₅₆O₅₆S₂

Molecular Weight

4190.64

MDL number

MFCD02687290

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Descriptions

Biochem/physiol Actions

Structural homolog of natiuretic peptides containing a 17 amino acid disulfide ring similar to ANP, BNP, and CNP that mediate their physiological effects through particulate guanylyl cyclase receptors generating cGMP.

Properties

assay

≥90% (HPLC)

storage temp.

−20°C

References

Reference

Collins, E., et al. J. Cardiovasc. Pharmacol. 35, 614, (2000)

Safety

Safety Statements

22-24/25

WGK Germany