L-Ethionine 

An analog of methionine that interferes with the normal methylation of DNA and other methylation pathways, and induces pancreatic toxicity and liver cancer. However, in animal studies, it has also been shown to act synergistically with methionine-depletion to block the growth and metastasis of methionine-dependent tumors.

~99% (TLC)

280 °C (dec.)(lit.)

Longnecker, D.S., Abnormal methyl metabolism in pancreatic toxicity and diabetes. J. Nutr. 132, 2373S-2376S, (2002)

Guo, H., et al., Methionine depletion modulates the antitumor and antimetastatic efficacy of ethionine. Anticancer Res. 16, 2719-2723, (1996)

Poirier, L.A., The effects of diet, genetics and chemicals on toxicity and aberrant DNA methylation: an introduction. J. Nutr. 132, 2336S-2339S, (2002)

Merck 13,3774

Beil. 4,III,1643

Corp MSDS 1, 1550:B / FT-IR 2 (1), 941:C / FT-IR 1 (1), 595:C / IR-Spectra (3), 354:D / NMR-Reference 2 (1), 502:A / RegBook 1 (1), 675:C / Sax 6, 218 / Sigma FT-IR 1 (1), 158:C / Structure Index 1, 101:B:9

3

ES6825300