Monoclonal Anti-Elastin antibody produced in mouse 

bovine α-elastin.

The antibody binds to insoluble elastin, α-elastin, tropoelastin (the soluble non-cross linked precursor of elastin) and to peptide fragments generated by proteolytic digestion of insoluble elastin. In tropoelastin preparations, three immunoreactive bands have been observed at 67.5 kDa, 65 kDa and 62 kDa corresponding to the three elastin isoforms. The antibody is specific for an epitope composed of the repeated sequence in elastin: Val-Gly-Val-Ala-Pro-Gly. This epitope has been shown to be a chemoattractant for fibroblasts and monocytes.

ascites fluid

BA-4

antigen mol wt 67.5 kDa

15 mM sodium azide

bovine, human, goat, canine, feline, guinea pig, pig, sheep

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:5,000 using sheep arterial tissue

microarray: suitable

IgG1

human ... ELN(2006)

dry ice

−20°C

Wrenn, D.S., et al. Biochemistry 25, 5172, (1986) abstract

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XP725, Panorama^® Antibody Microarray - XPRESS Profiler725 Kit