E8152
Sigma

EphA3/Fc Chimera from mouse

>90% (SDS-PAGE), recombinant, expressed in mouse NSO cells, lyophilized powder

Synonym

Cek4

Hek4

Hek

Mek4

Tyro4

MDL number

MFCD01867521

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Descriptions

Analysis Note

The biological activity is measured by its ability to bind recombinant human ephrin-A5/Fc in an ELISA.

Biochem/physiol Actions

Member of the Eph receptor tyrosine kinase family shown to bind ephrin-A1, ephrin-A2, ephrin-A3, ephrin-A4, ephrin-A5, and ephrin-B1; involved in pattern formation and morphogenesis.

Other Notes

Extracellular domain of mouse EphA3 (amino acids 1-541) fused by means of a polypeptide linker to the Fc region of human IgG1 that is histidine tagged at the C-terminus.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Properties

recombinant

expressed in mouse NSO cells

assay

>90% (SDS-PAGE)

form

lyophilized powder

mol wt

monomer calculated mol wt 86 kDa

mol wt ~110 kDa by SDS-PAGE (reducing)