E8277
Sigma

EphA4/Fc Chimera from mouse

>95% (SDS-PAGE), recombinant, expressed in mouse NSO cells, lyophilized powder

Synonym

Cek8

Hek8

Sek1

Sek

Tyro1

MDL number

MFCD01867522

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Descriptions

Analysis Note

The biological activity is measured by its ability to bind recombinant human ephrin-A5 in an ELISA assay.

Biochem/physiol Actions

Member of the Eph receptor tyrosine kinase family shown to bind ephrin-A1, ephrin-A2, ephrin-A3, ephrin-A4, ephrin-A5, ephrin-B2, and ephrin-B3; involved in pattern formation and morphogenesis. EphA4 can be detected in B cells, T cells, and keratinocytes.

General description

Extracellular domain of mouse EphA4 (amino acids 1-547) fused to the C-terminal 6X histidine-tagged Fc region of human IgG1 via a polypeptide linker.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Properties

recombinant

expressed in mouse NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

mol wt