E8402
Sigma

EphA5/Fc Chimera from rat

>95% (SDS-PAGE), recombinant, expressed in mouse NSO cells, lyophilized powder

Synonym

Bsk

Cek7

Ehk1

Hek7

Rek7

MDL number

MFCD01868353

Expand/Collapse All

Descriptions

Analysis Note

The biological activity is measured by its ability to bind recombinant mouse ephrin-A2/Fc in an ELISA assay.

Biochem/physiol Actions

Member of the Eph receptor tyrosine kinase family shown to bind ephrin-A1, ephrin-A2, ephrin-A3, ephrin-A4, and ephrin-A5; involved in pattern formation and morphogenesis.

General description

Extracellular domain of rat EphA5 (amino acids 1-573) fused by means of a polypeptide linker to the Fc region of human IgG1 that is histidine-tagged at the C-terminus.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Properties

recombinant

expressed in mouse NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

mol wt

monomer calculated mol wt 84 kDa

mol wt ~110 kDa by SDS-PAGE (reducing)