E8652
Sigma

EphA7/Fc Chimera from mouse

>90% (SDS-PAGE), recombinant, expressed in mouse NSO cells, lyophilized powder

Synonym

Cek11

Ebk

Ehk3

Hek11

Mdk1

MDL number

MFCD01867524

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Descriptions

Analysis Note

The biological activity is measured by its ability to bind recombinant human ephrin-A4/Fc in an ELISA assay.

Biochem/physiol Actions

Member of the Eph receptor tyrosine kinase family shown to bind ephrin-A1, ephrin-A2, ephrin-A3, ephrin-A4, and ephrin-A5; involved in pattern formation and morphogenesis.

Other Notes

Extracellular domain of mouse EphA7 (amino acids 1-549) fused by means of a polypeptide linker to the Fc region of human IgG1 that is histidine-tagged at the C-terminus.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Properties

recombinant

expressed in mouse NSO cells

assay

>90% (SDS-PAGE)

form

lyophilized powder

mol wt

monomer calculated mol wt 85.7 kDa

mol wt ~110 kDa by SDS-PAGE (reducing)