F6300
Sigma

Flumazenil

>99% (HPLC), solid

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Synonym

Ro�15-1788

Molecular Formula

C₁₅H₁₄FN₃O₃

Molecular Weight

303.29

CAS Number

78755-81-4

MDL number

MFCD00242764

PubChem Substance ID

24278437

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Descriptions

Biochem/physiol Actions

Highly specific benzodiazepine receptor antagonist.

Properties

assay

>99% (HPLC)

form

solid

color

white

Gene Information

human ... BZRAP1(9256), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA5(2558), GABRA6(2559), GABRG2(2566)

rat ... Gabra2(29706), Gabrg1(140674)

storage temp.

2-8°C

References

Reference

Bertz, R.J., et al., Effect of neuroactive steroids on [3H]flumazenil binding to the GABAA receptor complex in vitro. Neuropharmacology 34, 1169-1175, (1995) abstract

Hosoi, R., et al., Discrepancy of benzodiazepine receptor occupancy between 3H-flumazenil and 125I-iomazenil in intact mouse brain. J. Neural Transm. 106, 243-256, (1999) abstract

Przegalinski, E., et al., The influence of the benzodiazepine receptor antagonist flumazenil on the anxiolytic-like effects of CGP 37849 and ACPC in rats. Neuropharmacology 39, 1858-1864, (2000) abstract

Safety

WGK Germany

RTECS

NI2922170

Related Categories

... Pharmacologicals > Benzodiazepines and Anxiolytics

MSDS

Certificate of Analysis

Certificate of Origin

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