F7301
Sigma

Fibroblast Growth Factor-18 human

>95% (SDS-PAGE and HPLC), recombinant, expressed in Escherichia coli, lyophilized powder

Synonym

FGF-18

MDL number

MFCD01867042

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Descriptions

Analysis Note

The biological activity is determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors.

Physical form

Lyophilized from a 0.2 μm filtered solution in 10 mM Tris, pH 8.0.

Biochem/physiol Actions

FGF-18 is a heparin binding growth factor, which stimulates the proliferation and activation of cells that express the FGF receptors.

Properties

recombinant

expressed in Escherichia coli

assay

>95% (SDS-PAGE and HPLC)

form

lyophilized powder

mol wt

predicted mol wt 21.2 kDa

total impurities

Endotoxin, tested

Gene Information

human ... FGF18(8817)

storage temp.

−20°C

References

Reference

Hu, M., et al. Mol. Biol. Cell 18, 6063, (1998)

Ohbayashi, N. J. Biol. Chem. 273, 18161, (1998)

Safety

Safety Statements

22-24/25

WGK Germany

Related Categories

... Hematopoietic Stem Cell Expansion/Differentiation > Cytokine/Growth Factor

... Fibroblast Growth Factors (FGF) > FGF

... Receptor Tyrosine Kinases > Fibroblast Growth Factor Receptor (FGFR)

... Cytokines/Growth Factors/Chemokines > Growth Factors

F7301 - Datasheet (95kb)

MSDS

Certificate of Analysis

Certificate of Origin

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F7301 (Sigma)