G007
Sigma

Guvacine hydrochloride

≥97% (NMR), solid

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Molecular Formula

C₆H₉NO₂ · HCl

Molecular Weight

163.60

CAS Number

6027-91-4

MDL number

MFCD00055191

PubChem Substance ID

24278163

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Descriptions

Biochem/physiol Actions

GABA uptake inhibitor.

Preparation Note

Solutions may be stored for several days at 4 °C.

Properties

assay

≥97% (NMR)

form

solid

color

white

solubility

H₂O: soluble

ethanol: slightly soluble

Gene Information

human ... FGF9(2254), GABBR1(2550), GABBR2(9568), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

References

Reference

Rovira, et al., Somatic and dendritic and dendritic actions of gamma-aminobutyric acid agonist and uptake blockers in the hippocampus in vivo. Neuroscience 12, 543, (1984) abstract

Krause, et al., Dose-conductance relationships for GABA agonists and the effect of uptake inhibitors in crayfish stretch receptor neurons. Brain Res. 225, 319, (1981) abstract

Johnston, et al., Betel nut constituents as inhibitors of gamma-aminobutyric acid uptake. Nature 258, 6228, (1975)

Safety

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany