Biochem/physiol Actions
Gelsolin is an actin-severing protein found in mammalian cells and blood plasma. Exhibits tumor suppressor activity in several cancer cell lines and in nude mice.
Packaging
Package size based on protein content
Unit Definition
One unit will reduce viscosity difference between actin solution and buffer by 50% in a 1 mL mixture containing 1-2 mg F-actin, 0.15 M KCl, 20 mM Tris, pH 7.6, 0.2 mM CaCl2, 0.2 mM ATP and 1 mM DTT at 28°C.
Physical form
Lyophilized powder containing Tris buffer salts, pH 7.6, NaCl, DTT, and EGTA
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