G5773
Sigma

Galanin porcine

≥97% (HPLC), powder

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Amino Acid Sequence

Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-His-Asp-Lys-Tyr-Gly-Leu-Ala-NH₂

Molecular Formula

C₁₄₆H₂₁₃N₄₃O₄₀

Molecular Weight

3210.52

CAS Number

88813-36-9

MDL number

MFCD00133353

PubChem Substance ID

24895230

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Descriptions

Biochem/physiol Actions

Co-localized with acetylcholine and inhibits its release; inhibits the release of glutamic acid, decreases excitability of spinal neurons; blocks voltage-activated Ca²⁺ channels; linked to behavioral and cognitive deficits in Alzheimer's disease.

Properties

assay

≥97% (HPLC)

form

powder

Gene Information

pig ... GAL(397465)

storage temp.

−20°C

References

Reference

Ohman, A., et al., NMR study of the conformation and localization of porcine galanin in SDS micelles. Comparison with an inactive analog and a galanin receptor antagonist. Biochemistry 37, 9169-9178, (1998) abstract

Vento, P., et al., Nerve terminals containing neuropeptides decrease in number after massive proximal small bowel resection in the piglet. Dig. Dis. Sci. 43, 1102-1110, (1998) abstract

Korolkiewicz, R., et al., Contractile effects of porcine galanin(1-29)-NH2 on the rat isolated gastric fundus: mediation by potassium ions. Pharmacol. Res. 36, 147-151, (1997) abstract

Safety

WGK Germany

Related Categories

... Neuropeptides > Galanins

Galanin Receptors (190 kb)

MSDS

Certificate of Analysis

More Information