G6025
Sigma

Geranylgeranyl pyrophosphate ammonium salt

solution, ≥95% (TLC), ~1 mg/mL in methanol: NH₄OH (7:3)

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Synonym

all trans-3,7,11,15-Tetramethyl-2,6,10,14-hexadecatetraenyl pyrophosphate ammonium salt

GGPP

Molecular Formula

C₂₀H₃₆O₇P₂ · xNH₃

Molecular Weight

450.44 (free acid basis)

CAS Number

6699-20-3 (free acid)

MDL number

MFCD00156114

PubChem Substance ID

24895243

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Descriptions

Biochem/physiol Actions

Isoprenoid from the intracellular mevalonate pathway used for prenylation of several low molecular weight G proteins, including Ras. Intermediate in terpene biosynthesis.

Properties

assay

≥95% (TLC)

form

solution

packaging

vial of 200 μg

concentration

~1 mg/mL in methanol: NH₄OH (7:3)

storage temp.

−20°C

References

Reference

Massy, et al., Importance of geranylgeranyl pyrophosphate for mesangial cell DNA synthesis. Kidney Int. (Suppl.) 71, S80-S83, (1999) abstract

Seabra, et al., Prenylation assays for small GTPases. Methods Mol. Biol. 84, 251-260, (1998) abstract

Safety

Hazard Codes

F,T

Risk Statements

11-23/24/25-39/23/24/25

Safety Statements

7-16-36/37-45

RIDADR

UN 1230 3/PG 2

WGK Germany

Flash Point(F)

52 °F

Flash Point(C)

11 °C

Related Categories

... Cofactor > Isoprenoid

... Metabolites and Cofactors on the Metabolic Pathways Chart > Lipid

... Metabolic Libraries > Lipid Library

... G Protein Function > Post-translational Modification

Related Information

Protein Prenyltransferases (182 kb)

MSDS

Certificate of Analysis

Certificate of Origin

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G6025 (Sigma)

Geranylgeranyl pyrophosphate ammonium salt

solution, ≥95% (TLC), ~1 mg/mL in methanol: NH4OH (7:3)

solution, ≥95% (TLC), ~1 mg/mL in methanol: NH₄OH (7:3)