Galectin-1 human 

Galectin-1 has been implicated in metastasis and aggregation of cancer cells based on its association with the glycoprotein 90K.^1,2 Galectin-1 may play a significant role in cancer through apoptosis, cell adhesion and migration, regulation of the cell cycle and tumor evasion of immune responses.³

Galectin-1 is a member of the family of animal lectins, which selectively binds β-galactoside residues.

Lyophilized from a 5 mg/mL solution in phosphate buffered saline containing 8 mM DTT and 150 mM lactose.

expressed in Escherichia coli

≥95% (SDS-PAGE)

lyophilized powder

human ... LGALS1(3956)

−20°C

1. Grassadonia, A., et al., 90K (Mac-2 BP) and galectins in tumor progression and metastasis. Glycoconj. J. 19, 551-6, (2004)

2. Tinari, N., et al., Glycoprotein 90K/MAC-2BP interacts with galectin-1 and mediates galectin-1-induced cell aggregation. Int. J. Cancer 91, 167-72, (2001)

3. Rabinovich, G.A., Galectin-1 as a potential cancer target. (Review) Br. J. Cancer 92, 1188-92, (2005)

Pace, K.E., et al., Preparation of recombinant human galectin-1 and use in T-cell death assays. Methods Enzymol. 363, 499-518, (2003)