G8291
Sigma

Glu-Val-Asn-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyloctanoyl]-Ala-Glu-Phe

>93% (HPLC), solid

Synonym

OM99-2

Molecular Formula

C₄₁H₆₄N₈O₁₄

Molecular Weight

892.99

CAS Number

314266-76-7

MDL number

MFCD03452932

Descriptions

Biochem/physiol Actions

Inhibitor of brain β-secretase

Properties

assay

>93% (HPLC)

form

solid

storage temp.

−20°C

References

Reference

Ghosh, A.K., Design of potent inhibitors for human brain memapsin (β-secretase). J. Am. Chem. Soc. 122, 3522, (2000)

Ghosh, A.K., Structure of the protease domain of memapsin (β-secretase) complexed with inhibitor. Science 290, 150, (2000) abstract

Safety

Safety Statements

22-24/25

WGK Germany

Related Categories

... Protease Inhibitor Specificity Index > β-Secretase

... R to Z > beta-Secretase

... Enzyme Inhibitors > beta-Secretase

... Alzheimers and Neurodegenerative Disease Research > Other

... Neurodegenerative Disease Peptides > Other Alzheimer’s Peptides

MSDS

Certificate of Analysis

Related Categories

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G8291 (Sigma)