H0536
Sigma

Hepatocyte Growth Factor Receptor (c-Met)/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Synonym

HGF Receptor (c-Met)

MDL number

MFCD01867051

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Descriptions

Analysis Note

The biological activity is measured by its ability to bind human HGF.

Biochem/physiol Actions

Heterodimeric transmembrane glycoprotein with binding capacity for c-Met. Activation of this receptor has been correlated with induction of the Ras pathway.

Other Notes

Extracellular domain of c-Met fused to the C-terminal 6X histidine-tagged Fc region of human IgG1.

Physical form

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing 5 mg bovine serum albumin.

Properties

recombinant

expressed in NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

mol wt

calculated mol wt 129 kDa

total impurities

Endotoxin, tested

Gene Information

human ... MET(4233)

storage temp.

−20°C

References

Reference

Park, M., et al. Proc. Natl. Acad. Sci. USA 84, 6379, (1987) abstract

Safety

WGK Germany

Related product

H0540, Anti-Hepatocyte Growth Factor antibody produced in goat

H0665, Monoclonal Anti-Hepatocyte Growth Factor antibody produced in mouse

Related Categories

... Islet Stem Cell Differentiation > Growth Factors

... Cytokines and Growth Factors > Hepatocyte Growth Factor/Scatter Factor

... Receptor Tyrosine Kinases > Met

H0536 - Datasheet (26kb)

MSDS

Certificate of Analysis

Certificate of Origin

More Information