H158
Sigma

[des-Arg¹⁰]-HOE 140

synthetic, >98%, powder

Synonym

D-Arg-L-Arg-L-prolyl-L-Hyp-Gly-L-(2-thienyl)Ala-L-Ser-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3β,7aβ)-octahydro-1H-indole-2-carboxylic acid

Amino Acid Sequence

D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic

Molecular Formula

C₅₃H₇₇N₁₅O₁₂S

Molecular Weight

1148.34

MDL number

MFCD00213940

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Descriptions

Biochem/physiol Actions

Potent B₁ bradykinin receptor antagonist.

Properties

biological source

synthetic

assay

>98%

form

powder

color

white

storage temp.

−20°C

References

Reference

Wirth, et al., Des Arg¹⁰ [Hoe 140] is a potent B₁ bradykinin antagonist. Agents and Actions (Suppl.) 38, 406, (1992)

Rhaleb, et al., Non-selectivity of new bradykinin antagonists for B₁ receptors. Life Sci. 51, PL125-PL129, (1992) abstract

Safety

WGK Germany

Related Categories

... Neuropeptides > Bradykinins

... Peptides for Cell Biology > Bradykinins

Bradykinin Receptors (178 kb)

MSDS

Certificate of Analysis

More Information

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