H7250
Sigma

Histamine dihydrochloride

≥99% (TLC), powder

zoom

1 of 1

Synonym

2-(4-Imidazolyl)ethylamine dihydrochloride

Molecular Formula

C₅H₉N₃ · 2HCl

Molecular Weight

184.07

CAS Number

56-92-8

Beilstein Registry Number

3624116

MDL number

MFCD00012703

PubChem Substance ID

24277777

EG/EC Number

200-298-4

Expand/Collapse All

Descriptions

Packaging

10 mg in autosmp vl

Biochem/physiol Actions

Endogenous H₁ and H₂ histamine receptor agonist; H₁ activation mobilizes Ca²⁺; H₂ activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.

Properties

assay

≥99% (TLC)

form

powder

color

white to off-white

249-252 °C(lit.)

Gene Information

human ... HRH1(3269), HRH2(3274)

storage temp.

2-8°C

References

Reference

Fu, L.W., et al., Endogenous histamine stimulates ischemically sensitive abdominal visceral afferents through H1 receptors. Am. J. Physiol. 273(6 Pt 2), 2726, (1997)

Merck

Merck 13,4739

Beilstein

Beil. 25,IV,2049

reference

FT-IR 2 (3), 3513:B / FT-IR 1 (2), 617:D / IR-Spectra (3), 1220:D / IR-Spectra (2), 1062:E / NMR-Reference 2 (2), 489:B / RegBook 1 (2), 2357:I / Sax 6, 1535 / Sigma FT-IR 1 (2), 16:C / Structure Index 1, 373:A:4

Safety

Hazard Codes

Risk Statements

36/37/38-42/43

Safety Statements

22-26-36/37/39-45

WGK Germany

RTECS

MS1575000

1-8-9