H8645
Sigma

(1S,9R)-(+)-β-Hydrastine

1 of 1

Molecular Formula

C₂₁H₂₁NO₆

Molecular Weight

383.39

CAS Number

29617-43-4

MDL number

MFCD00132881

PubChem Substance ID

24278171

Descriptions

Biochem/physiol Actions

Potent competitive GABA_A receptor antagonist which is more potent than bicuculline; isolated from Corydalis stricta.

Properties

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

storage temp.

−20°C

References

Reference

Huang, et al., (+)-Hydrastine a potent competitive antagonist at mammalian GABA_A receptors. Br. J. Pharmacol. 99, 727, (1990) abstract

Safety

WGK Germany

Related Categories

... GABAergics > Antagonists

... Ligand-Gated Ion Channels > GABA and Glycine Receptor Modulators

MSDS

Certificate of Analysis

Related Categories

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H8645 (Sigma)