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Human Cytogenetics: Malignancy and acquired abnormalities, A Practical Approach, 3rd ed.

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General description

The advent of molecular technologies has lead to a rapid acceleration in the cytogenetic study of malignancy and acquired abnormalities. As well as having a chapter devoted to molecular technologies (FISH, PRINS, and CGH), molecular methodology is emphasized in all chapters. There are three chapters on the specific methodology for the cytogenetic study of myeloid leukemia, acute lymphoblastic leukemia, and lymphomas and lymphoproliferative disorders. Also covered are chromosome instability syndromes, mutagen-induced chromosome damage in lymphocytes and the role of cytogenetics in the assessment of hematological disorders.

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Identifiers

ISBN-10

0-19-963841-1

ISBN-13

978-0-19-963841-3

Properties

publication info

D.E. Rooney, ed., Oxford University Press, 2001, 287 pp., soft cover

Table of Contents

1. Basic techniques for the preparation and analysis of chromosomes from bone marrow and leukaemic blood, B. Czepulkowski
2. Cytogenetics in myeloid leukaemia, A. M. Potter and A. Watmore
3. Cytogenetics in acute lymphoblastic leukaemia, B. Czepulkowski and B. Gibbons
4. The lymphomas and chronic lymphoid leukaemias, C. J. Harrison
5. The role of cytogenetics in the diagnosis and classification of haematological neoplasms, B. J. Bain
6. Molecular cytogenetic technologies, L. Kearney and D. W. Hammond
7. Methods in solid tumour cytogenetics, N. Mandahl
8. In vivo mutagen-induced chromosome damage in human lymphocytes, E. J. Tawn and C. A. Whitehouse
9. Chromosome instability syndromes, R. T. Howell
Appendix 1: List of suppliers
Appendix 2: Safety considerations
Appendix 3: Ideograms of G-banded chromosomes at three levels of resolution
Appendix 4: Glossary
Index