Iturin A from Bacillus subtilis 

Iturin A exhibits strong antifungal activity against pathogenic yeast and fungi.¹ It interacts with the cytoplasmic membrane of the target cell forming ion conducting pores² and its mode of action could be attributed to its interaction with sterols and phospholipids. The compound causes the release of exo-vesicles from human erythrocytes.³

A family of lipopeptides characterized by a heptapeptide cyclized with a C₁₃-C₁₇ β-amino fatty acid. Composed mainly of C₁₄-C₁₅ β-amino acids.

≥90% (HPLC)

2-8°C

1. Klich, M.A., et al. Mycopathologia 127, 123, (1994) abstract

2. Maget-Dana, R., et al. Toxicology 87, 151, (1994) abstract

3. Thimon, L., et al. Cytobios. 79, 96, (1994)

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