I4402
Sigma

Insulin-like Growth Factor Binding Protein-4 human

>97% (SDS-PAGE), recombinant, expressed in mouse NSO cells, lyophilized powder

Synonym

IGFBP-4

MDL number

MFCD01867062

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Descriptions

Analysis Note

The biological activity is measured by its ability to inhibit activity of recombinant human IGF-1 or recombinant human IGF-II on MCF-7 cells.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 50 μg bovine serum albumin per 1 μg of cytokine.

Properties

recombinant

expressed in mouse NSO cells

assay

>97% (SDS-PAGE)

form

lyophilized powder

mol wt

mol wt 25 kDa by SDS-PAGE (non-reducing)

mol wt 32 kDa by SDS-PAGE (reducing)

purified by

affinity chromatography (IGF-I ligand)

total impurities

Endotoxin, tested

storage temp.

−20°C

References

Reference

Karey, K. P., et al., Differential responsiveness of human breast cancer cell lines MCF-7 and T47D to growth factors and 17 beta-estradiol. Cancer Res. 48, 4083, (1988) abstract

Safety

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

Related Categories

... Insulin-like Growth Factors (IGF) > IGF Binding Proteins

... Receptor Tyrosine Kinases > Insulin Receptor (IR)

I4402 - Datasheet (56kb)

I4402 - Enzyme Assay (27kb)

MSDS

Certificate of Analysis

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I4402 (Sigma)