I5270
Sigma

Anti-Interleukin-11 antibody produced in goat

IgG fraction of antiserum, lyophilized powder

Synonym

Anti-IL-11

MDL number

MFCD00212981

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Descriptions

Immunogen

recombinant human IL-11 expressed in Sf 21 insect cells.

Preparation Note

Purified using protein G.

Specificity

The antibody neutralizes the biological activity of recombinant human IL-11.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Properties

antibody form

IgG fraction of antiserum

form

lyophilized powder

species reactivity

human

application(s)

neutralization: suitable

Gene Information

human ... IL11(3589)

storage temp.

−20°C

References

Reference

Schoenhaut, D.S., et al., Cloning and expression of murine IL-12. J. Immunol. 148, 3433-3440, (1992) abstract

Stern, A.S., et al., Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells. Proc. Natl. Acad. Sci. USA 87, 6808-6812, (1990) abstract

Trinchieri, G., et al., Natural killer cell stimulatory factor (NKSF) or interleukin-12 is a key regulator of immune response and inflammation. Progress in Growth Factor Research 4, 355-368, (1992) abstract

Kobayashi, M., et al., Identification and purification of natural killer cell stimulatory factor (NKSF) a cytokine with multiple biologic effects on human lymphocytes. J. Exp. Med. 170, 827-845, (1989) abstract

Safety

WGK Germany