I5277
Sigma

Interferon-γ Receptor 1 human

>95% (SDS-PAGE), recombinant, expressed in mouse NSO cells, lyophilized powder

Synonym

IFN-γ R 1

MDL number

MFCD03457243

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Descriptions

Analysis Note

The bioactivity is measured by its ability to inhibit recombinant human IFN-γ mediated protection of Hela cells to viral lysis.

Biochem/physiol Actions

Recombinant human IFN-γ receptors are comprised of two type I membrane proteins, IFN-γ R1 and IFN-γ R2. Both are members of the type II cytokine receptor family. IFN-γ R1 binds IFN-γ ligand and is a potent IFN-γ antagonist.

Linkage

Mouse and human IFN-γ share 52% homology.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5.0 mg bovine serum albumin.

Properties

recombinant

expressed in mouse NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

mol wt

glycosylated form mol wt 40-50 kDa by electrophoresis

total impurities

Endotoxin, tested

Gene Information

human ... IFNGR1(3459)

storage temp.

−20°C

References

Reference

Meager, A., Clemens, J., ed. Lymphokines and Interferons, A Practical Approach Oxford , (1987)

Related Categories

... Hematopoietic Stem Cell Expansion/Differentiation > Cytokine/Growth Factor

... Interferons (IFN) > IFN-γ

... Stem Cell Differentiation > Receptors

... Stem Cell Characterization > Receptors for Stem Cell Biology

I5277 - Datasheet (52kb)

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Certificate of Analysis

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I5277 (Sigma)