K2882
Sigma

Monoclonal Anti-Ku Antigen antibody produced in mouse

clone Ku15, ascites fluid

MDL number

Descriptions

Antigen Background

Ku protein binds to DNase-sensitive regions of chromatin where it appears to be involved in DNA-dependent protein kinase-mediated DNA replication, transcription, or repair.

Immunogen

preparation of human carcinoma cell line A431. Recognizes an epitope included within amino acids 490-707.

Properties

antibody form

ascites fluid

clone

Ku15

mol wt

antigen mol wt 86 kDa

contains

15 mM sodium azide

species reactivity

human, monkey

application(s)

immunoblotting: suitable

immunocytochemistry: suitable

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable

immunohistochemistry (frozen sections): suitable

immunoprecipitation: suitable

indirect immunofluorescence: 1:10,000 using cultured human fibroblasts

microarray: suitable

isotype

IgG1

Gene Information

human ... XRCC6(2547)

shipped in

dry ice

storage temp.

−20°C

Safety

WGK Germany

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Related Categories

... Functional Profiling of Stem Cells > Antibodies for Epigenetics

... Enzymes > Antibodies to DNA Synthesis and Repair Enzymes

... Antibodies for Gene Regulation and Expression > Antibodies to Nuclear Proteins

... Antibodies for Gene Regulation and Expression > Antibodies to Transcription Regulators

... Alphabetical Index > K

... Clone Index > K

K2882 - Datasheet (31kb)

MSDS

Certificate of Analysis

More Information